| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
|---|
| Ligand | BDBM85099 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_33104 (CHEMBL645957) |
|---|
| Kd | 1000±n/a nM |
|---|
| Citation |  Nozulak, J; Kalkman, HO; Floersheim, P; Hoyer, D; Schoeffter, P; Buerki, HR (+)-cis-4,5,7a,8,9,10,11,11a-octahydro-7H-10-methylindolo[1,7- bc][2,6]-naphthyridine: a 5-HT2C/2B receptor antagonist with low 5-HT2A receptor affinity. J Med Chem38:28-33 (1995) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-1A adrenergic receptor |
|---|
| Name: | Alpha-1A adrenergic receptor |
|---|
| Synonyms: | ADA1A_BOVIN | ADRA1A | ADRA1C | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha-1C adrenergic receptor | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 51492.08 |
|---|
| Organism: | CALF |
|---|
| Description: | adrenergic Alpha1 0 CALF |
|---|
| Residue: | 466 |
|---|
| Sequence: | MVFLSGNASDSSNCTHPPPPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNVWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
AQVGGSGVTSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FRPSETVFKIAFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRKQSSKHTLGYTL
HAPSHVLEGQHKDLVRIPVGSAETFYKISKTDGVCEWKIFSSLPRGSARMAVARDPSACT
TARVRSKSFLQVCCCLGPSTPSHGENHQIPTIKIHTISLSENGEEV
|
|
|
|---|
| BDBM85099 |
|---|
| n/a |
|---|
| Name | BDBM85099 |
|---|
| Synonyms: | CAS_141474-54-6 | SDZ SER 082 FUMARATE | SDZ SER-082 | SER-082 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H20N2 |
|---|
| Mol. Mass. | 228.3327 |
|---|
| SMILES | CN1CC[C@@H]2CN3CCc4cccc([C@@H]2C1)c34 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
