Reaction Details |
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Target | Leukotriene B4 receptor 2 |
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Ligand | BDBM50472436 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_99657 (CHEMBL704423) |
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IC50 | >10000±n/a nM |
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Citation | Poudrel, JM; Hullot, P; Vidal, JP; Girard, JP; Rossi, JC; Muller, A; Bonne, C; Bezuglov, V; Serkov, I; Renard, P; Pfeiffer, B Synthesis and structure-activity relationships of new 1, 3-disubstituted cyclohexanes as structurally rigid leukotriene B(4) receptor antagonists. J Med Chem42:5289-310 (1999) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Leukotriene B4 receptor 2 |
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Name: | Leukotriene B4 receptor 2 |
Synonyms: | BLT2R | BLTR2 | LT4R2_HUMAN | LTB4 receptor JULF2 | LTB4-R 2 | LTB4-R2 | LTB4R2 | LTB4R2 protein | Leukotriene B4 | Leukotriene B4 R2 | Leukotriene B4 receptor | Leukotriene B4 receptor 2 | Leukotriene B4 receptor BLT2 | Leukotriene b1 | Seven transmembrane receptor BLTR2 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 37964.86 |
Organism: | Homo sapiens (Human) |
Description: | Leukotriene 2 0 HUMAN::Q9NPC1 |
Residue: | 358 |
Sequence: | MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATL
VLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRC
LAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAAA
HLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPY
HAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAG
PRFLTRLFEGSGEARGGGRSREGTMELRTTPQLKVVGQGRGNGDPGGGMEKDGPEWDL
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BDBM50472436 |
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n/a |
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Name | BDBM50472436 |
Synonyms: | CHEMBL2112037 |
Type | Small organic molecule |
Emp. Form. | C20H27NaO4 |
Mol. Mass. | 354.4157 |
SMILES | [Na;v0+].[#8]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-c1ccccc1)\[#6]=[#6]\[#6@H]-1-[#6]-[#6]-[#6][C@]([#8])([#6]1)[#6](-[#8-])=O |r| |
Structure |
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