| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
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| Ligand | BDBM50027023 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_33092 |
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| Ki | 1600±n/a nM |
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| Citation |  Saari, WS; Halczenko, W; King, SW; Huff, JR; Guare, JP; Hunt, CA; Randall, WC; Anderson, PS; Lotti, VJ; Taylor, DA Pyridinylpiperazines, a new class of selective alpha 2-adrenoceptor antagonists. J Med Chem26:1696-701 (1984) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Alpha-1A adrenergic receptor |
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| Name: | Alpha-1A adrenergic receptor |
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| Synonyms: | ADA1A_BOVIN | ADRA1A | ADRA1C | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha-1C adrenergic receptor | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51492.08 |
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| Organism: | CALF |
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| Description: | adrenergic Alpha1 0 CALF |
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| Residue: | 466 |
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| Sequence: | MVFLSGNASDSSNCTHPPPPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNVWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
AQVGGSGVTSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FRPSETVFKIAFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRKQSSKHTLGYTL
HAPSHVLEGQHKDLVRIPVGSAETFYKISKTDGVCEWKIFSSLPRGSARMAVARDPSACT
TARVRSKSFLQVCCCLGPSTPSHGENHQIPTIKIHTISLSENGEEV
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| BDBM50027023 |
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| n/a |
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| Name | BDBM50027023 |
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| Synonyms: | 1-(3-Iodo-pyridin-2-yl)-piperazine | CHEMBL295764 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H12IN3 |
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| Mol. Mass. | 289.1162 |
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| SMILES | Ic1cccnc1N1CCNCC1 |
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| Structure | 
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