| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
|---|
| Ligand | BDBM50130272 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_3725 (CHEMBL619897) |
|---|
| Ki | 5.2±n/a nM |
|---|
| Citation |  Kikuchi, C; Nagaso, H; Hiranuma, T; Koyama, M Tetrahydrobenzindoles: selective antagonists of the 5-HT7 receptor. J Med Chem42:533-5 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 7 |
|---|
| Name: | 5-hydroxytryptamine receptor 7 |
|---|
| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 53573.08 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P34969 |
|---|
| Residue: | 479 |
|---|
| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
|
|
|
|---|
| BDBM50130272 |
|---|
| n/a |
|---|
| Name | BDBM50130272 |
|---|
| Synonyms: | 2a-[3-(4-Phenyl-piperazin-1-yl)-propyl]-2a,3,4,5-tetrahydro-1H-benzo[cd]indol-2-one | CHEMBL13052 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H29N3O |
|---|
| Mol. Mass. | 375.5066 |
|---|
| SMILES | O=C1Nc2cccc3CCCC1(CCCN1CCN(CC1)c1ccccc1)c23 |
|---|
| Structure | 
|
|---|
Search and Browse
