| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphoglycerate kinase 1 |
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| Ligand | BDBM14487 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_152781 (CHEMBL765582) |
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| IC50 | 3000000±n/a nM |
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| Citation |  Bressi, JC; Choe, J; Hough, MT; Buckner, FS; Van Voorhis, WC; Verlinde, CL; Hol, WG; Gelb, MH Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine. J Med Chem43:4135-50 (2000) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphoglycerate kinase 1 |
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| Name: | Phosphoglycerate kinase 1 |
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| Synonyms: | Cell migration-inducing gene 10 protein | PGK1 | PGK1_HUMAN | PGKA | PGKA | PRP 2 | Phosphoglycerate kinase 1 | Primer recognition protein 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44619.74 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_104832 |
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| Residue: | 417 |
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| Sequence: | MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL
MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE
NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN
LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM
AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ
ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV
KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI
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| BDBM14487 |
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| n/a |
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| Name | BDBM14487 |
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| Synonyms: | (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol | Adenine-beta-D-arabinofuranoside | Adenosine | CHEMBL477 | N6-Methylado | [U-14C]adenosine | cid_191 | cid_60961 |
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| Type | Nucleoside or nucleotide |
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| Emp. Form. | C10H13N5O4 |
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| Mol. Mass. | 267.2413 |
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| SMILES | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |
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| Structure | 
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