| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1B adrenergic receptor |
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| Ligand | BDBM50473678 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_34489 (CHEMBL647201) |
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| Ki | 15±n/a nM |
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| Citation |  Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW 2-(Anilinomethyl)imidazolines as alpha1 adrenergic receptor agonists: the discovery of alpha1a subtype selective 2'-alkylsulfonyl-substituted analogues. J Med Chem45:2229-39 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1B adrenergic receptor |
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| Name: | Alpha-1B adrenergic receptor |
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| Synonyms: | ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 56862.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35368 |
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| Residue: | 520 |
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| Sequence: | MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFV
RILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRT
LPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLT
EPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
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| BDBM50473678 |
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| n/a |
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| Name | BDBM50473678 |
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| Synonyms: | CHEMBL306792 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H14FN3S |
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| Mol. Mass. | 239.312 |
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| SMILES | CSc1cc(F)ccc1NCC1=NCCN1 |t:12| |
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| Structure | 
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