| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1D adrenergic receptor |
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| Ligand | BDBM50473677 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_32576 (CHEMBL643414) |
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| EC50 | 0.912011±n/a nM |
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| Citation |  Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW 2-(Anilinomethyl)imidazolines as alpha1 adrenergic receptor agonists: the discovery of alpha1a subtype selective 2'-alkylsulfonyl-substituted analogues. J Med Chem45:2229-39 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1D adrenergic receptor |
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| Name: | Alpha-1D adrenergic receptor |
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| Synonyms: | ADA1D_HUMAN | ADRA1A | ADRA1D | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1D-adrenoceptor | Alpha 1D-adrenoreceptor | Alpha adrenergic receptor (1a and 1d) | Alpha-1D adrenoceptor | Alpha-adrenergic receptor 1a | adrenergic Alpha1D |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 60485.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | adrenergic Alpha1D ADRA1D HUMAN::P25100 |
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| Residue: | 572 |
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| Sequence: | MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAG
SGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILS
VACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCC
TASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVP
PDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKAS
EVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLC
WFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQ
CRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEM
QAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVE
AVSLGVPHEVAEGATCQAYELADYSNLRETDI
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| BDBM50473677 |
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| n/a |
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| Name | BDBM50473677 |
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| Synonyms: | CHEMBL72441 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H17N3S |
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| Mol. Mass. | 235.348 |
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| SMILES | CSc1ccc(C)cc1NCC1=NCCN1 |t:12| |
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| Structure | 
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