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TargetMuscarinic acetylcholine receptor M2
LigandBDBM81939
Substrate/Competitorn/a
Meas. Tech.ChEMBL_140026 (CHEMBL745569)
EC50 30974±n/a nM
Citation Stiefl, NBaumann, K Mapping property distributions of molecular surfaces: algorithm and evaluation of a novel 3D quantitative structure-activity relationship technique. J Med Chem46:1390-407 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Muscarinic acetylcholine receptor M2
Name:Muscarinic acetylcholine receptor M2
Synonyms:ACM2_PIG | CHRM2 | Cholinergic, muscarinic | GPM2 | LOC100715343 | Muscarinic acetylcholine receptor M2 | Muscarinic receptor 2
Type:Enzyme Catalytic Domain
Mol. Mass.:51688.65
Organism:GUINEA PIG
Description:Cholinergic, muscarinic 0 GUINEA PIG::P06199
Residue:466
Sequence:
MNNSTNSSNSGLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQEPVSPSLVQGRI
VKPNNNNMPGSDEALEHNKIQNGKAPRDAVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIKIVTKTQKSDSCTPANTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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  Blast E-value cutoff:
BDBM81939
n/a
NameBDBM81939
Synonyms:CAS_52-53-9 | NSC_62969 | VERAPAMIL
TypeSmall organic molecule
Emp. Form.C27H38N2O4
Mol. Mass.454.6016
SMILESCOc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC
Structure
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