| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
|---|
| Ligand | BDBM50475875 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_388187 (CHEMBL865447) |
|---|
| Ki | 1.000000±n/a nM |
|---|
| Citation |  Chimenti, F; Secci, D; Bolasco, A; Chimenti, P; Granese, A; Carradori, S; Befani, O; Turini, P; Alcaro, S; Ortuso, F Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of N,N'-bis[2-oxo-2H-benzopyran]-3-carboxamides. Bioorg Med Chem Lett16:4135-40 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] A |
|---|
| Name: | Amine oxidase [flavin-containing] A |
|---|
| Synonyms: | AOFA_BOVIN | Amine oxidase [flavin-containing] A | MAO-A | MAOA | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A | Monoamine oxidase type A |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 59764.63 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_1501477 |
|---|
| Residue: | 527 |
|---|
| Sequence: | MESLQKTSDAGQMFDVVVIGGGISGLSAAKLLAEHEVNVLVLEARERVGGRTYTVRNEHV
DYVDVGGAYVGPTQNRILRLSKQLGLETYKVNVNERLVHYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTMDNMGKEIPADAPWEAPHAVEWDKMTMKDLIEKICWTKTARQFASLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSITNGGQERKFVGGSGQVSERIMQLLGDRVKL
RSPVTYVDQSSENITVETLNRELYECRYVISAIPPTLTAKIHFRPELPSERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEEAPISITLDDTKPDGSLPAIMGFILARKADR
LAKVHKDIRKRKICELYAKVLGSQEALHPVHYEEKNWCQEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKLSAKDIWIQEPEAED
VPAVEITPSFWERNLPSVSGLLKIVGFSTSITALWFVMYRFRLLSRS
|
|
|
|---|
| BDBM50475875 |
|---|
| n/a |
|---|
| Name | BDBM50475875 |
|---|
| Synonyms: | CHEMBL212501 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H20N2O6 |
|---|
| Mol. Mass. | 432.4254 |
|---|
| SMILES | O=C(NCCCCNC(=O)c1cc2ccccc2oc1=O)c1cc2ccccc2oc1=O |
|---|
| Structure | 
|
|---|
Search and Browse
