| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
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| Ligand | BDBM50417350 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_429548 (CHEMBL918089) |
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| Ki | 28±n/a nM |
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| Citation |  Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A alpha 2-adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha 2C-subtype. J Med Chem47:6160-73 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-2A adrenergic receptor |
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| Name: | Alpha-2A adrenergic receptor |
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| Synonyms: | ADA2A_HUMAN | ADRA2A | ADRA2R | ADRAR | Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens] |
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| Type: | Enzyme |
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| Mol. Mass.: | 48979.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08913 |
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| Residue: | 465 |
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| Sequence: | MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLML
LTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAW
CEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVIS
FPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKR
RTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGP
RDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTP
AAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPR
TLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
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| BDBM50417350 |
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| n/a |
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| Name | BDBM50417350 |
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| Synonyms: | CHEMBL374584 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18N2O2 |
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| Mol. Mass. | 282.337 |
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| SMILES | CC(Oc1ccccc1-c1cccc(O)c1)C1=NCCN1 |t:18| |
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| Structure | 
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