| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2B adrenergic receptor |
|---|
| Ligand | BDBM50417350 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_429545 (CHEMBL918086) |
|---|
| Ki | 355±n/a nM |
|---|
| Citation |  Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A alpha 2-adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha 2C-subtype. J Med Chem47:6160-73 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-2B adrenergic receptor |
|---|
| Name: | Alpha-2B adrenergic receptor |
|---|
| Synonyms: | ADA2B_HUMAN | ADRA2B | ADRA2L1 | ADRA2RL1 | Adrenergic alpha2B | Adrenergic receptor | Adrenergic receptor alpha | Adrenergic, alpha-2B-, receptor [Homo sapiens] | Alpha-2 adrenergic receptor subtype C2 | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | Alpha-2BAR |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 49964.20 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P18089 |
|---|
| Residue: | 450 |
|---|
| Sequence: | MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRR
AQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSS
LNPVIYTIFNQDFRRAFRRILCRPWTQTAW
|
|
|
|---|
| BDBM50417350 |
|---|
| n/a |
|---|
| Name | BDBM50417350 |
|---|
| Synonyms: | CHEMBL374584 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H18N2O2 |
|---|
| Mol. Mass. | 282.337 |
|---|
| SMILES | CC(Oc1ccccc1-c1cccc(O)c1)C1=NCCN1 |t:18| |
|---|
| Structure | 
|
|---|
Search and Browse
