Reaction Details |
| Report a problem with these data |
Target | Pepsin A |
---|
Ligand | BDBM50025509 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEBML_154017 |
---|
Ki | 3.5±n/a nM |
---|
Citation | Rich, DH; Salituro, FG Synthesis of analogues of pepstatin. Effect of structure in subsites P1', P2', and P2 on inhibition of porcine pepsin. J Med Chem26:904-10 (1983) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Pepsin A |
---|
Name: | Pepsin A |
Synonyms: | PEPA_PIG | PGA | Pepsin | Pepsin A precursor |
Type: | Enzyme |
Mol. Mass.: | 41232.87 |
Organism: | Porcine |
Description: | n/a |
Residue: | 385 |
Sequence: | MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALI
GDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDS
STFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGIL
GLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNW
VPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENS
DGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWIL
GDVFIRQYYTVFDRANNKVGLAPVA
|
|
|
BDBM50025509 |
---|
n/a |
---|
Name | BDBM50025509 |
Synonyms: | 2-(3-Hydroxy-6-methyl-4-{3-methyl-2-[3-methyl-2-(3-methyl-butyrylamino)-butyrylamino]-butyrylamino}-heptanoylamino)-propionic acid methyl ester | CHEMBL3143644 |
Type | Small organic molecule |
Emp. Form. | C27H50N4O7 |
Mol. Mass. | 542.7085 |
SMILES | COC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(C)C |r| |
Structure |
|