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TargetUrease subunit beta
LigandBDBM50099857
Substrate/Competitorn/a
Meas. Tech.ChEMBL_443632 (CHEMBL893891)
IC50 18000±n/a nM
Citation Xiao, ZP; Shi, DH; Li, HQ; Zhang, LN; Xu, C; Zhu, HL Polyphenols based on isoflavones as inhibitors of Helicobacter pylori urease. Bioorg Med Chem15:3703-10 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Urease subunit beta
Name:Urease subunit beta
Synonyms:3.5.1.5 | URE1_HELPY | Urea amidohydrolase subunit beta | Urease subunit beta | hpuB | ureB
Type:PROTEIN
Mol. Mass.:61676.43
Organism:Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori)
Description:ChEMBL_117195
Residue:569
Sequence:
MKKISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNN
PSKEELDLIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEA
LAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGGTGPADGTNATTITPGRRNLK
WMLRAAEEYSMNLGFLAKGNASNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADK
YDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPAST
NPTIPFTVNTEAEHMDMLMVCHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITS
SDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGIS
EYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFA
HHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNP
ETYHVFVDGKEVTSKPANKVSLAQLFSIF
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  Blast E-value cutoff:
BDBM50099857
n/a
NameBDBM50099857
Synonyms:ACETOHYDROXAMIC ACID (AHA) | AHA | Acethydroxamsaeure | Acethydroxamsaure | Acetic acid, oxime | Acetylhydroxamic acid | Cetohyroxamic acid | Lithostat | Methylhydroxamic acid | N-Acetyl hydroxyacetamide | N-Acetylhydroxylamine | N-Hydroxyacetamide | acetohydroxamic acid
TypeSmall organic molecule
Emp. Form.C2H5NO2
Mol. Mass.75.0666
SMILESCC(=O)NO
Structure
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