| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1C |
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| Ligand | BDBM50476624 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_444320 (CHEMBL893556) |
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| EC50 | 16±n/a nM |
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| Citation |  Faust, R; Garratt, PJ; Trujillo Pérez, MA; Piccio, VJ; Madsen, C; Stenstrĝm, A; Frĝlund, B; Davidson, K; Teh, MT; Sugden, D 7-Substituted-melatonin and 7-substituted-1-methylmelatonin analogues: effect of substituents on potency and binding affinity. Bioorg Med Chem15:4543-51 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1C |
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| Name: | Melatonin receptor type 1C |
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| Synonyms: | MTR1C_XENLA | Melatonin 1C | Melatonin receptor 1C | Melatonin receptor type 1C | mtnr1c |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47442.40 |
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| Organism: | Xenopus |
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| Description: | Melatonin 1C 0 Xenopus::P49219 |
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| Residue: | 420 |
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| Sequence: | MMEVNSTCLDCRTPGTIRTEQDAQDSASQGLTSALAVVLIFTIVVDVLGNILVILSVLRN
KKLQNAGNLFVVSLSIADLVVAVYPYPVILIAIFQNGWTLGNIHCQISGFLMGLSVIGSV
FNITAIAINRYCYICHSLRYDKLYNQRSTWCYLGLTWILTIIAIVPNFFVGSLQYDPRIF
SCTFAQTVSSSYTITVVVVHFIVPLSVVTFCYLRIWVLVIQVKHRVRQDFKQKLTQTDLR
NFLTMFVVFVLFAVCWAPLNFIGLAVAINPFHVAPKIPEWLFVLSYFMAYFNSCLNAVIY
GVLNQNFRKEYKRILMSLLTPRLLFLDTSRGGTEGLKSKPSPAVTNNNQADMLGEARSLW
LSRRNGAKMVIIIRPRKAQIAIIHQIFWPQSSWATCRQDTKITGEEDGCRELCKDGISQR
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| BDBM50476624 |
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| n/a |
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| Name | BDBM50476624 |
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| Synonyms: | CHEMBL233516 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H22N2O2 |
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| Mol. Mass. | 274.3581 |
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| SMILES | CCC(=O)NCCc1cn(C)c2c(C)cc(OC)cc12 |
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| Structure | 
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