| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50176019 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_446505 (CHEMBL895619) |
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| Ki | 0.501187±n/a nM |
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| Citation |  Lange, JH; Reinders, JH; Tolboom, JT; Glennon, JC; Coolen, HK; Kruse, CG Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs. J Med Chem50:5103-8 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50176019 |
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| n/a |
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| Name | BDBM50176019 |
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| Synonyms: | (R)-8-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazin-1-yl)-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one | (R)-8-{4-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-piperazin-1-yl}-2-methyl-4H-benzo[1,4]oxazin-3-one | CHEMBL196514 | SLV-314 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27FN4O2 |
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| Mol. Mass. | 422.4952 |
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| SMILES | C[C@H]1Oc2c(NC1=O)cccc2N1CCN(CCCc2c[nH]c3ccc(F)cc23)CC1 |
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| Structure | 
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