Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetP2Y purinoceptor 11
LigandBDBM50477239
Substrate/Competitorn/a
Meas. Tech.ChEMBL_451010 (CHEMBL900091)
EC50 1288±n/a nM
Citation Greve, HMeis, SKassack, MUKehraus, SKrick, AWright, ADKönig, GM New iantherans from the marine sponge Ianthella quadrangulata: novel agonists of the P2Y(11) receptor. J Med Chem50:5600-7 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
P2Y purinoceptor 11
Name:P2Y purinoceptor 11
Synonyms:P2RY11 | P2Y purinoceptor 11 | P2Y11 | P2Y11_HUMAN | Purinergic receptor P2Y11
Type:PROTEIN
Mol. Mass.:40366.02
Organism:Homo sapiens (Human)
Description:ChEMBL_1362532
Residue:374
Sequence:
MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRP
WHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFI
TCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNC
SVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTV
AEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPY
VGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATA
APKPSEPQSRELSQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50477239
n/a
NameBDBM50477239
Synonyms:ISO-IANTHERAN A
TypeSmall organic molecule
Emp. Form.C32H16Br4Na2O12S2
Mol. Mass.1022.188
SMILES[Na;v0+].[Na;v0+].[#8]-c1ccc(cc1Br)-c1cc2cc(\[#6]=[#6](/[#8]S([#8-])(=O)=O)\[#6](\[#8]S([#8-])(=O)=O)=[#6]\c3cc(Br)c4oc(cc4c3)-c3ccc(-[#8])c(Br)c3)cc(Br)c2o1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: