| Reaction Details |
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 | Report a problem with these data |
| Target | Ornithine decarboxylase |
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| Ligand | BDBM50028197 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_148131 |
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| Ki | 39000±n/a nM |
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| Citation |  Bey, P; Gerhart, F; Van Dorsselaer, V; Danzin, C alpha-(Fluoromethyl)dehydroornithine and alpha-(fluoromethyl)dehydroputrescine analogues as irreversible inhibitors of ornithine decarboxylase. J Med Chem26:1551-6 (1983) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Ornithine decarboxylase |
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| Name: | Ornithine decarboxylase |
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| Synonyms: | DCOR_RAT | Odc | Odc1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51037.04 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1344641 |
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| Residue: | 461 |
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| Sequence: | MGSFTKEEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDVLKKHLRWLKALP
RVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPPERIIYANPCKQVSQI
KYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLL
LERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMGTEVGFSMYLLDIGGGFPG
SEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ
TGSDDEDESNEQTLMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTC
DGLDRIVERCSLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRSMWQLMKQI
QSHGFPPEVEEQDVGTLPMSCAQESGMDRHPAACASASINV
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| BDBM50028197 |
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| n/a |
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| Name | BDBM50028197 |
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| Synonyms: | 2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNITHINE |
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| Type | Small organic molecule |
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| Emp. Form. | C6H12F2N2O2 |
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| Mol. Mass. | 182.1685 |
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| SMILES | NCCCC(N)(C(F)F)C(O)=O |
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| Structure | 
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