| Reaction Details |
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 | Report a problem with these data |
| Target | Protease |
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| Ligand | BDBM50067593 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_491043 (CHEMBL982903) |
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| Ki | 0.120000±n/a nM |
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| Citation |  Kozísek, M; Cígler, P; Lepsík, M; Fanfrlík, J; Rezácová, P; Brynda, J; Pokorná, J; Plesek, J; Grüner, B; Grantz Sasková, K; Václavíková, J; Král, V; Konvalinka, J Inorganic polyhedral metallacarborane inhibitors of HIV protease: a new approach to overcoming antiviral resistance. J Med Chem51:4839-43 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protease |
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| Name: | Protease |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 10904.79 |
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| Organism: | Human immunodeficiency virus 1 (HIV-1) |
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| Description: | Q9YQ12 |
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| Residue: | 99 |
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| Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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|
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| BDBM50067593 |
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| n/a |
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| Name | BDBM50067593 |
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| Synonyms: | CHEBI:44032 | Crixivan | Indinavir | L-735524 | MK-639 | US10806794, Compound Indinavir |
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| Type | Small organic molecule |
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| Emp. Form. | C36H47N5O4 |
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| Mol. Mass. | 613.7895 |
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| SMILES | CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 |r| |
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| Structure | 
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