| Reaction Details |
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 | Report a problem with these data |
| Target | Pepsin A |
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| Ligand | BDBM50025530 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_154018 |
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| Ki | 8.6±n/a nM |
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| Citation |  Rich, DH; Bernatowicz, MS Synthesis of analogues of the carboxyl protease inhibitor pepstatin. Effect of structure in subsite P3 on inhibition of pepsin. J Med Chem25:791-5 (1982) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Pepsin A |
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| Name: | Pepsin A |
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| Synonyms: | PEPA_PIG | PGA | Pepsin | Pepsin A precursor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41232.87 |
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| Organism: | Porcine |
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| Description: | n/a |
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| Residue: | 385 |
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| Sequence: | MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALI
GDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDS
STFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGIL
GLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNW
VPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENS
DGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWIL
GDVFIRQYYTVFDRANNKVGLAPVA
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| BDBM50025530 |
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| n/a |
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| Name | BDBM50025530 |
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| Synonyms: | BDBM50028390 | CHEMBL166522 | [1-(1-{1-Hydroxy-2-[1-(3-methyl-butylcarbamoyl)-ethylcarbamoyl]-ethyl}-3-methyl-butylcarbamoyl)-2-methyl-propyl]-carbamic acid isopropyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C25H48N4O6 |
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| Mol. Mass. | 500.6718 |
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| SMILES | CC(C)CCNC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C |
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| Structure | 
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