| Reaction Details |
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 | Report a problem with these data |
| Target | HIV-1 protease |
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| Ligand | BDBM12883 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_517306 (CHEMBL1031359) |
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| Ki | 0.006000±n/a nM |
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| Citation |  Jorissen, RN; Reddy, GS; Ali, A; Altman, MD; Chellappan, S; Anjum, SG; Tidor, B; Schiffer, CA; Rana, TM; Gilson, MK Additivity in the analysis and design of HIV protease inhibitors. J Med Chem52:737-54 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| HIV-1 protease |
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| Name: | HIV-1 protease |
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| Synonyms: | HIV-1 | HIV-1 protease | protease |
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| Type: | PROTEIN |
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| Mol. Mass.: | 10795.19 |
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| Organism: | Human immunodeficiency virus |
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| Description: | ChEMBL_118439 |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF
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| BDBM12883 |
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| n/a |
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| Name | BDBM12883 |
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| Synonyms: | (5S)-3-(3-Acetylphenyl)-N-[(1S,2R)-3-[[(benzo[1,3]dioxole-5-sulfonyl)](isobutyl)amino]-1-benzyl-2-hydroxypropyl]-2-oxooxazolidine-5-carboxamide | (5S)-N-[(2S,3R)-4-[2H-1,3-benzodioxole-5-(2-methylpropyl)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]-3-(3-acetylphenyl)-2-oxo-1,3-oxazolidine-5-carboxamide | N-Aryl-oxazolidinone-5-carboxamide Analogue 26e |
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| Type | Small organic molecule |
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| Emp. Form. | C33H37N3O9S |
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| Mol. Mass. | 651.727 |
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| SMILES | CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(C(=O)O1)c1cccc(c1)C(C)=O)S(=O)(=O)c1ccc2OCOc2c1 |r| |
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| Structure | 
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