| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50010216 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_521749 (CHEMBL1005039) |
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| IC50 | 1660±n/a nM |
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| Citation |  Mandal, AS; Roy, K Predictive QSAR modeling of HIV reverse transcriptase inhibitor TIBO derivatives. Eur J Med Chem44:1509-24 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
|
|
|
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| BDBM50010216 |
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| n/a |
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| Name | BDBM50010216 |
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| Synonyms: | 7-propyl-8-methyl-6,7,8,9-tetrahydro-2H-2,7,9a-triaza-benzo[cd]azulene-1-thione | 8-Methyl-7-propyl-6,7,8,9-tetrahydro-2H-2,7,9a-triaza-benzo[cd]azulene-1-thione | CHEMBL67451 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H19N3S |
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| Mol. Mass. | 261.386 |
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| SMILES | CCCN1Cc2cccc3[nH]c(=S)n(CC1C)c23 |
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| Structure | 
|
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