| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM1732 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_545024 (CHEMBL1016320) |
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| IC50 | 2697739±n/a nM |
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| Citation |  Hu, R; Doucet, JP; Delamar, M; Zhang, R QSAR models for 2-amino-6-arylsulfonylbenzonitriles and congeners HIV-1 reverse transcriptase inhibitors based on linear and nonlinear regression methods. Eur J Med Chem44:2158-71 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM1732 |
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| n/a |
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| Name | BDBM1732 |
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| Synonyms: | 2-Amino-6-arylthiobenzonitrile deriv. 1b | 2-amino-6-[(2-methoxyphenyl)sulfanyl]benzonitrile |
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| Type | Small organic molecule |
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| Emp. Form. | C14H12N2OS |
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| Mol. Mass. | 256.323 |
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| SMILES | COc1ccccc1Sc1cccc(N)c1C#N |
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| Structure | 
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