| Reaction Details |
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 | Report a problem with these data |
| Target | Stromelysin-3 |
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| Ligand | BDBM50482225 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_638696 (CHEMBL1168920) |
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| IC50 | 2900000±n/a nM |
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| Citation |  Abdel-Mohsen, HT; Ragab, FA; Ramla, MM; El Diwani, HI Novel benzimidazole-pyrimidine conjugates as potent antitumor agents. Eur J Med Chem45:2336-44 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Stromelysin-3 |
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| Name: | Stromelysin-3 |
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| Synonyms: | MMP11_MOUSE | Matrix metalloproteinase 11 | Mmp11 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55452.62 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_106453 |
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| Residue: | 492 |
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| Sequence: | MARAACLLRAISRVLLLPLPLLLLLLLLLPSPLMARARPPESHRHHPVKKGPRLLHAALP
NTLTSVPASHWVPSPAGSSRPLRCGVPDLPDVLNARNRQKRFVLSGGRWEKTDLTYRILR
FPWQLVREQVRQTVAEALQVWSEVTPLTFTEVHEGRADIMIDFARYWHGDNLPFDGPGGI
LAHAFFPKTHREGDVHFDYDETWTIGDNQGTDLLQVAAHEFGHVLGLQHTTAAKALMSPF
YTFRYPLSLSPDDRRGIQHLYGRPQMAPTSPAPTLSSQAGTDTNEIALLEPETPPDVCET
SFDAVSTIRGELFFFKAGFVWRLRSGRLQPGYPALASRHWQGLPSPVDAAFEDAQGQIWF
FQGAQYWVYDGEKPVLGPAPLSKLGLQGSPVHAALVWGPEKNKIYFFRGGDYWRFHPRTQ
RVDNPVPRRSTDWRGVPSEIDAAFQDAEGYAYFLRGHLYWKFDPVKVKVLEGFPRPVGPD
FFDCAEPANTFR
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| BDBM50482225 |
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| n/a |
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| Name | BDBM50482225 |
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| Synonyms: | CHEMBL1165091 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H27N7OS |
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| Mol. Mass. | 545.657 |
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| SMILES | O=C(CN1CCN(CC1)c1nc(SCc2nc3ccccc3[nH]2)nc(-c2ccccc2)c1C#N)c1ccccc1 |
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| Structure | 
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