| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protease |
|---|
| Ligand | BDBM50483092 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_685646 (CHEMBL1285548) |
|---|
| Ki | 0.003000±n/a nM |
|---|
| Citation |  Ali, A; Reddy, GS; Nalam, MN; Anjum, SG; Cao, H; Schiffer, CA; Rana, TM Structure-based design, synthesis, and structure-activity relationship studies of HIV-1 protease inhibitors incorporating phenyloxazolidinones. J Med Chem53:7699-708 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protease |
|---|
| Name: | Protease |
|---|
| Synonyms: | n/a |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 10904.79 |
|---|
| Organism: | Human immunodeficiency virus 1 (HIV-1) |
|---|
| Description: | Q9YQ12 |
|---|
| Residue: | 99 |
|---|
| Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
|---|
| BDBM50483092 |
|---|
| n/a |
|---|
| Name | BDBM50483092 |
|---|
| Synonyms: | CHEMBL1276087 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H36N4O8S3 |
|---|
| Mol. Mass. | 700.845 |
|---|
| SMILES | CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(C(=O)O1)c1cccc(c1)S(C)(=O)=O)S(=O)(=O)c1ccc2ncsc2c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
