| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50370655 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_712672 (CHEMBL1660415) |
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| Ki | 630±n/a nM |
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| Citation |  Yang, G; Paintsil, E; Dutschman, GE; Grill, SP; Wang, CJ; Wang, J; Tanaka, H; Hamasaki, T; Baba, M; Cheng, YC Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile. Antimicrob Agents Chemother53:4640-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50370655 |
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| n/a |
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| Name | BDBM50370655 |
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| Synonyms: | CHEMBL485652 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H15N2O13P3 |
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| Mol. Mass. | 464.153 |
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| SMILES | Cc1cn([C@@H]2O[C@H](CO[P@@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)C=C2)c(=O)[nH]c1=O |r,c:21| |
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| Structure | 
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