| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM2177 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_758401 (CHEMBL1811267) |
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| IC50 | 5390±n/a nM |
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| Citation |  Bode, ML; Gravestock, D; Moleele, SS; van der Westhuyzen, CW; Pelly, SC; Steenkamp, PA; Hoppe, HC; Khan, T; Nkabinde, LA Imidazo[1,2-a]pyridin-3-amines as potential HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorg Med Chem19:4227-37 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM2177 |
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| n/a |
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| Name | BDBM2177 |
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| Synonyms: | SM27 | US8501787, 163 |
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| Type | n/a |
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| Emp. Form. | C20H22ClN3 |
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| Mol. Mass. | 339.862 |
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| SMILES | Cc1ccc2nc(c(NC3CCCCC3)n2c1)-c1ccccc1Cl |
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| Structure | 
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