| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50484326 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_771986 (CHEMBL1837306) |
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| Ki | 3100±n/a nM |
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| Citation |  Novikov, MS; Ivanova, ON; Ivanov, AV; Ozerov, AA; Valuev-Elliston, VT; Temburnikar, K; Gurskaya, GV; Kochetkov, SN; Pannecouque, C; Balzarini, J; Seley-Radtke, KL 1-[2-(2-Benzoyl- and 2-benzylphenoxy)ethyl]uracils as potent anti-HIV-1 agents. Bioorg Med Chem19:5794-802 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50484326 |
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| n/a |
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| Name | BDBM50484326 |
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| Synonyms: | CHEMBL1835500 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21BrN2O3 |
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| Mol. Mass. | 429.307 |
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| SMILES | Cc1cc(C)cc(Cc2cc(Br)ccc2OCCn2ccc(=O)[nH]c2=O)c1 |
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| Structure | 
|
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