| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 13 |
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| Ligand | BDBM50485275 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_823871 (CHEMBL2045668) |
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| IC50 | 14000±n/a nM |
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| Citation |  de Oliveira Lopes, R; Romeiro, NC; de Lima, CK; Louback da Silva, L; de Miranda, AL; Nascimento, PG; Cunha, FQ; Barreiro, EJ; Lima, LM Docking, synthesis and pharmacological activity of novel urea-derivatives designed as p38 MAPK inhibitors. Eur J Med Chem54:264-71 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitogen-activated protein kinase 13 |
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| Name: | Mitogen-activated protein kinase 13 |
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| Synonyms: | MAP kinase 13 | MAP kinase p38 delta | MAPK 13 | MK13_MOUSE | Mapk13 | Mitogen-activated protein kinase 13 | Mitogen-activated protein kinase p38 delta | Serk4 | Stress-activated protein kinase 4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42081.17 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_105000 |
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| Residue: | 366 |
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| Sequence: | MSLTRKRGFYKQDINKTAWELPKTYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMHHENVIGLLDVFTPASSLRSFHDFYLVMPFMQTDLQKIMGM
EFSEDKVQYLVYQMLKGLKYIHSAGIVHRDLKPGNLAVNEDCELKILDFGLARHTDTEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGAEFVQKLKDKAAKSYIQSLPQSPKKDFTQLFPRASPQAADLLDKMLELDVDKRLTAA
QALAHPFFEPFRDPEEETEAQQPFDDALEHEKLSVDEWKQHIYKEISNFSPIARKDSRRR
SGMKLQ
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| BDBM50485275 |
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| n/a |
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| Name | BDBM50485275 |
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| Synonyms: | CHEMBL2043204 | LASSBio-998 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N3O5 |
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| Mol. Mass. | 385.4137 |
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| SMILES | CCOC(=O)c1cc2cc3OCOc3cc2nc1NC(=O)NC1CCCCC1 |
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| Structure | 
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