| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 22 member 6 |
|---|
| Ligand | BDBM50485561 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_837479 (CHEMBL2075967) |
|---|
| IC50 | 718000±n/a nM |
|---|
| Citation |  Uwai, Y; Saito, H; Inui, K Rat renal organic anion transporter rOAT1 mediates transport of urinary-excreted cephalosporins, but not of biliary-excreted cefoperazone. Drug Metab Pharmacokinet17:125-9 (2002) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier family 22 member 6 |
|---|
| Name: | Solute carrier family 22 member 6 |
|---|
| Synonyms: | Oat1 | Organic anion transporter 1 | S22A6_RAT | Slc22a6 | rOAT1 | rROAT1 | renal organic anion transporter 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60784.17 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_838479 |
|---|
| Residue: | 551 |
|---|
| Sequence: | MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPHHCRPPANANLSKD
GGLEAWLPLDKQGQPESCLRFTSPQWGPPFYNGTEANGTRVTEPCIDGWVYDNSTFPSTI
VTEWNLVCSHRAFRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA
YAPNYTVYCVFRLLSGMSLASIAINCMTLNVEWMPIHTRAYVGTLIGYVYSLGQFLLAGI
AYAVPHWRHLQLVVSVPFFIAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEE
GAKLSIEVLRTSLQKELTLSKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL
QGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQMASLLLAGICILVNGIIPKSHT
IIRTSLAVLGKGCLASSFNCIFLYTGELYPTVIRQTGLGMGSTMARVGSIVSPLVSMTAE
FYPSMPLFIFGAVPVVASAVTALLPETLGQPLPDTVQDLKSRSRGKQNQQQQEQQKQMMP
LQASTQEKNGL
|
|
|
|---|
| BDBM50485561 |
|---|
| n/a |
|---|
| Name | BDBM50485561 |
|---|
| Synonyms: | CHEBI:355510 | Cefotiam | Ceradon | J01DC07 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H23N9O4S3 |
|---|
| Mol. Mass. | 525.628 |
|---|
| SMILES | [H][C@]12SCC(CSc3nnnn3CCN(C)C)=C(N1C(=O)[C@H]2NC(=O)Cc1csc(N)n1)C(O)=O |c:17| |
|---|
| Structure | 
|
|---|
Search and Browse
