Reaction Details | |||
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Target | ATP-binding cassette sub-family C member 2 | ||
Ligand | BDBM58924 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_836167 (CHEMBL2075066) | ||
Ki | 7600±n/a nM | ||
Citation | Bode, KA; Donner, MG; Leier, I; Keppler, D Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate. Biochem Pharmacol64:151-8 (2002) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
ATP-binding cassette sub-family C member 2 | |||
Name: | ATP-binding cassette sub-family C member 2 | ||
Synonyms: | ATP-binding cassette sub-family C member 2 | Abcc2 | Canalicular multidrug resistance protein | Canalicular multispecific organic anion transporter 1 | Cmoat | Cmrp | MRP2_RAT | Mrp2 | Multidrug resistance-associated protein 2 | ||
Type: | PROTEIN | ||
Mol. Mass.: | 173415.22 | ||
Organism: | Rattus norvegicus | ||
Description: | ChEMBL_1455464 | ||
Residue: | 1541 | ||
Sequence: |
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BDBM58924 | |||
n/a | |||
Name | BDBM58924 | ||
Synonyms: | (2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methyl-hept-5-enoic acid | (2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methyl-5-heptenoic acid | (2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid | (2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methyl-hept-5-enoic acid | Fusidic acid | MLS001332649 | SMR000857101 | cid_3000226 | ||
Type | Small organic molecule | ||
Emp. Form. | C31H48O6 | ||
Mol. Mass. | 516.7092 | ||
SMILES | [#6]-[#6@@H]-1-[#6@H](-[#8])-[#6]-[#6][C@@]2([#6])[#6@H]-1-[#6]-[#6][C@@]1([#6])[#6@H]2-[#6@H](-[#8])-[#6]-[#6@H]2\[#6](-[#6@H](-[#6][C@]12[#6])-[#8]-[#6](-[#6])=O)=[#6](/[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6](-[#8])=O | ||
Structure |