| Reaction Details |
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 | Report a problem with these data |
| Target | HIV-1 protease |
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| Ligand | BDBM50485764 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_858488 (CHEMBL2169287) |
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| Ki | 0.044000±n/a nM |
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| Citation |  Parai, MK; Huggins, DJ; Cao, H; Nalam, MN; Ali, A; Schiffer, CA; Tidor, B; Rana, TM Design, synthesis, and biological and structural evaluations of novel HIV-1 protease inhibitors to combat drug resistance. J Med Chem55:6328-41 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| HIV-1 protease |
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| Name: | HIV-1 protease |
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| Synonyms: | HIV-1 | HIV-1 protease | protease |
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| Type: | PROTEIN |
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| Mol. Mass.: | 10795.19 |
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| Organism: | Human immunodeficiency virus |
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| Description: | ChEMBL_118439 |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50485764 |
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| n/a |
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| Name | BDBM50485764 |
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| Synonyms: | CHEMBL2165912 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H37Cl2N3O7S |
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| Mol. Mass. | 618.57 |
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| SMILES | CC[C@H](C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OCCNC(=O)C(Cl)Cl)S(=O)(=O)c1ccc(OC)cc1 |r| |
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| Structure | 
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