| Reaction Details |
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 | Report a problem with these data |
| Target | Cellular tumor antigen p53 |
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| Ligand | BDBM50403665 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_876865 (CHEMBL2184459) |
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| Kd | 140000±n/a nM |
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| Citation |  Gavrin, LK; Denny, RA; Saiah, E Small molecules that target protein misfolding. J Med Chem55:10823-43 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cellular tumor antigen p53 |
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| Name: | Cellular tumor antigen p53 |
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| Synonyms: | Antigen NY-CO-13 | CREB-binding protein/p53 | GST-p53 | His6-p53 | P53 | P53_HUMAN | Phosphoprotein p53 | TP53 | Tumor Suppressor p53 |
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| Type: | fusion protein |
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| Mol. Mass.: | 43654.73 |
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| Organism: | Homo sapiens (Human) |
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| Description: | The full-length His6-wt-p53 expressed in E. coli was used in assays. |
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| Residue: | 393 |
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| Sequence: | MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGP
DEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAK
SVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE
RCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNS
SCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELP
PGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPG
GSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD
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| BDBM50403665 |
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| n/a |
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| Name | BDBM50403665 |
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| Synonyms: | CHEMBL1235116 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H18N2 |
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| Mol. Mass. | 238.3275 |
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| SMILES | CCn1c2ccccc2c2cc(CNC)ccc12 |
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| Structure | 
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