| Reaction Details |
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 | Report a problem with these data |
| Target | Dihydroorotate dehydrogenase (quinone), mitochondrial |
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| Ligand | BDBM15353 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_899894 (CHEMBL3062604) |
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| IC50 | 100±n/a nM |
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| Citation |  TBA Med Chem Res20:321-332 (2011) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dihydroorotate dehydrogenase (quinone), mitochondrial |
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| Name: | Dihydroorotate dehydrogenase (quinone), mitochondrial |
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| Synonyms: | DHOdehase | Dihydroorotate Dehydrogenase (DHODH) | Dihydroorotate dehydrogenase homolog | Dihydroorotate oxidase | PYRD_PLAF7 |
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| Type: | Enzyme |
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| Mol. Mass.: | 65581.88 |
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| Organism: | Plasmodium falciparum (isolate 3D7) |
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| Description: | Q08210 |
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| Residue: | 569 |
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| Sequence: | MISKLKPQFMFLPKKHILSYCRKDVLNLFEQKFYYTSKRKESNNMKNESLLRLINYNRYY
NKIDSNNYYNGGKILSNDRQYIYSPLCEYKKKINDISSYVSVPFKINIRNLGTSNFVNNK
KDVLDNDYIYENIKKEKSKHKKIIFLLFVSLFGLYGFFESYNPEFFLYDIFLKFCLKYID
GEICHDLFLLLGKYNILPYDTSNDSIYACTNIKHLDFINPFGVAAGFDKNGVCIDSILKL
GFSFIEIGTITPRGQTGNAKPRIFRDVESRSIINSCGFNNMGCDKVTENLILFRKRQEED
KLLSKHIVGVSIGKNKDTVNIVDDLKYCINKIGRYADYIAINVSSPNTPGLRDNQEAGKL
KNIILSVKEEIDNLEKNNIMNDESTYNEDNKIVEKKNNFNKNNSHMMKDAKDNFLWFNTT
KKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMIISNTTTQINDIKSFENKKGGVSGAK
LKDISTKFICEMYNYTNKQIPIIASGGIFSGLDALEKIEAGASVCQLYSCLVFNGMKSAV
QIKRELNHLLYQRGYYNLKEAIGRKHSKS
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| BDBM15353 |
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| n/a |
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| Name | BDBM15353 |
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| Synonyms: | 2-methyl-N-(naphthalen-1-yl)-3-nitrobenzamide | ChemBridge compound no. 8 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14N2O3 |
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| Mol. Mass. | 306.3154 |
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| SMILES | Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc2ccccc12 |
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| Structure | 
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