| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor gamma |
|---|
| Ligand | BDBM50029774 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_196325 (CHEMBL806268) |
|---|
| Kd | 3±n/a nM |
|---|
| Citation |  Johnson, AT; Klein, ES; Gillett, SJ; Wang, L; Song, TK; Pino, ME; Chandraratna, RA Synthesis and characterization of a highly potent and effective antagonist of retinoic acid receptors. J Med Chem38:4764-7 (1996) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor gamma |
|---|
| Name: | Retinoic acid receptor gamma |
|---|
| Synonyms: | NR1B3 | Nuclear receptor subfamily 1 group B member 3 | RAR-gamma | RARG | RARG_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoic acid receptor gamma | Retinoid receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 50345.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1458016 |
|---|
| Residue: | 454 |
|---|
| Sequence: | MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
|
|
|
|---|
| BDBM50029774 |
|---|
| n/a |
|---|
| Name | BDBM50029774 |
|---|
| Synonyms: | 4-(5,5-Dimethyl-8-p-tolyl-5,6-dihydro-naphthalen-2-ylethynyl)-benzoic acid | CHEMBL358145 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H24O2 |
|---|
| Mol. Mass. | 392.489 |
|---|
| SMILES | Cc1ccc(cc1)C1=CCC(C)(C)c2ccc(cc12)C#Cc1ccc(cc1)C(O)=O |t:8| |
|---|
| Structure | 
|
|---|
Search and Browse
