Ki Summary

Reaction Details

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Target

Scytalone dehydratase

Ligand

BDBM50486973

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_907765 (CHEMBL3065688)

16±n/a nM

Citation

Jennings, LD; Rayner, DR; Jordan, DB; Okonya, JF; Basarab, GS; Amorose, DK; Anaclerio, BM; Lee, JK; Schwartz, RS; Whitmore, KA Cyclobutane carboxamide inhibitors of fungal melanin: biosynthesis and their evaluation as fungicides. Bioorg Med Chem8:897-907 (2000) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Scytalone dehydratase

Name:

Scytalone dehydratase

Synonyms:

SCYD_MAGO7 | SDH1 | Scytalone dehydratase

Type:

PROTEIN

Mol. Mass.:

20248.63

Organism:

Magnaporthe grisea

Description:

ChEMBL_199536

Residue:

172

Sequence:

MGSQVQKSDEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEA
MPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKE
VTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK

BDBM50486973

n/a

Name

BDBM50486973

Synonyms:

CHEMBL2251866

Type

Small organic molecule

Emp. Form.

C15H20BrNO2

Mol. Mass.

326.229

SMILES

C[C@@H](NC(=O)[C@]1(C)C[C@@](C)(O)C1)c1ccc(Br)cc1 |r,wU:8.9,wD:5.4,1.0,(11.75,-47.57,;11.77,-49.11,;10.44,-49.9,;9.1,-49.14,;9.08,-47.6,;7.78,-49.92,;7.76,-51.46,;6.69,-51.02,;5.6,-49.94,;4.25,-50.7,;4.5,-48.84,;6.68,-48.84,;13.11,-49.87,;13.12,-51.41,;14.46,-52.16,;15.78,-51.38,;17.13,-52.13,;15.76,-49.83,;14.42,-49.08,)|

Structure