Ki Summary

Reaction Details

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Target

Scytalone dehydratase

Ligand

BDBM50486976

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_907765 (CHEMBL3065688)

44±n/a nM

Citation

Jennings, LD; Rayner, DR; Jordan, DB; Okonya, JF; Basarab, GS; Amorose, DK; Anaclerio, BM; Lee, JK; Schwartz, RS; Whitmore, KA Cyclobutane carboxamide inhibitors of fungal melanin: biosynthesis and their evaluation as fungicides. Bioorg Med Chem8:897-907 (2000) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Scytalone dehydratase

Name:

Scytalone dehydratase

Synonyms:

SCYD_MAGO7 | SDH1 | Scytalone dehydratase

Type:

PROTEIN

Mol. Mass.:

20248.63

Organism:

Magnaporthe grisea

Description:

ChEMBL_199536

Residue:

172

Sequence:

MGSQVQKSDEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEA
MPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKE
VTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK

BDBM50486976

n/a

Name

BDBM50486976

Synonyms:

CHEMBL2251857

Type

Small organic molecule

Emp. Form.

C14H17BrClNO

Mol. Mass.

330.648

SMILES

C[C@@H](NC(=O)[C@H]1C[C@@](C)(Cl)C1)c1ccc(Br)cc1 |r,wU:5.4,7.8,wD:1.0,(7.79,-27.66,;7.81,-29.2,;6.48,-29.98,;5.14,-29.23,;5.12,-27.69,;3.82,-30.01,;2.73,-31.11,;1.64,-30.02,;.3,-30.78,;.54,-28.92,;2.72,-28.93,;9.15,-29.96,;9.16,-31.49,;10.5,-32.25,;11.82,-31.46,;13.17,-32.22,;11.8,-29.92,;10.46,-29.17,)|

Structure