| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor DM1 |
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| Ligand | BDBM50008072 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_906756 (CHEMBL3051465) |
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| Ki | 2980±n/a nM |
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| Citation |  Honda, H; Tomizawa, M; Casida, JE Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists. J Agric Food Chem55:2276-81 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor DM1 |
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| Name: | Muscarinic acetylcholine receptor DM1 |
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| Synonyms: | ACM1_DROME | AcrC | Muscarinic acetylcholine receptor DM1 | mAChR-A | mAcR-60C | mAcR-60C |
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| Type: | PROTEIN |
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| Mol. Mass.: | 86647.10 |
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| Organism: | Drosophila melanogaster |
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| Description: | ChEMBL_106611 |
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| Residue: | 805 |
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| Sequence: | MEPVMSLALAAHGPPSILEPLFKTVTTSTTTTTTTTTSTTTTTASPAGYSPGYPGTTLLT
ALFENLTSTAASGLYDPYSGMYGNQTNGTIGFETKGPRYSLASMVVMGFVAAILSTVTVA
GNVMVMISFKIDKQLQTISNYFLFSLAIADFAIGAISMPLFAVTTILGYWPLGPIVCDTW
LALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRTTNRAAVMIGAAWGISLLLWPPWI
YSWPYIEGKRTVPKDECYIQFIETNQYITFGTALAAFYFPVTIMCFLYWRIWRETKKRQK
DLPNLQAGKKDSSKRSNSSDENTVVNHASGGLLAFAQVGGNDHDTWRRPRSESSPDAESV
YMTNMVIDSGYHGMHSRKSSIKSTNTIKKSYTCFGSIKEWCIAWWHSGREDSDDFAYEQE
EPSDLGYATPVTIETPLQSSVSRCTSMNVMRDNYSMGGSVSGVRPPSILLSDVSPTPLPR
PPLASISQLQEMSAVTASTTANVNTSGNGNGAINNNNNASHNGNGAVNGNGAGNGSGIGL
GTTGNATHRDSRTLPVINRINSRSVSQDSVYTILIRLPSDGASSNAANGGGGGPGAGAAA
SASLSMQGDCAPSIKMIHEDGPTTTAAAAPLASAAATRRPLPSRDSEFSLPLGRRMSHAQ
HDARLLNAKVIPKQLGKAGGGAAGGGVGGAHALMNARNAAKKKKKSQEKRQESKAAKTLS
AILLSFIITWTPYNILVLIKPLTTCSDCIPTELWDFFYALCYINSTINPMCYALCNATFR
RTYVRILTCKWHTRNREGMVRGVYN
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| BDBM50008072 |
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| n/a |
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| Name | BDBM50008072 |
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| Synonyms: | (+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one | (3S,4R)-3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone | (3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone | CHEMBL550 | ISOPTO CARPINE | PILOCARPINE | PILOCARPINE HYDROCHLORIDE |
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| Type | Small organic molecule |
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| Emp. Form. | C11H16N2O2 |
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| Mol. Mass. | 208.2569 |
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| SMILES | CC[C@H]1[C@@H](Cc2cncn2C)COC1=O |r| |
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| Structure | 
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