| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 3 |
|---|
| Ligand | BDBM50030519 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_141443 (CHEMBL750216) |
|---|
| IC50 | 231±n/a nM |
|---|
| Citation |  Michne, WF; Guiles, JW; Treasurywala, AM; Castonguay, LA; Weigelt, CA; Oconnor, B; Volberg, WA; Grant, AM; Chadwick, CC; Krafte, DS Novel inhibitors of potassium ion channels on human T lymphocytes. J Med Chem38:1877-83 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Potassium voltage-gated channel subfamily A member 3 |
|---|
| Name: | Potassium voltage-gated channel subfamily A member 3 |
|---|
| Synonyms: | HGK5 | HLK3 | HPCN3 | HuKIII | KCNA3 | KCNA3_HUMAN | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 63835.47 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1513935 |
|---|
| Residue: | 575 |
|---|
| Sequence: | MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
|
|
|
|---|
| BDBM50030519 |
|---|
| n/a |
|---|
| Name | BDBM50030519 |
|---|
| Synonyms: | CHEMBL53676 | [7-Chloro-1-(3,4-dichloro-benzyl)-1H-quinolin-(4E)-ylidene]-hexyl-amine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H23Cl3N2 |
|---|
| Mol. Mass. | 421.79 |
|---|
| SMILES | CCCCCC\N=c1/ccn(Cc2ccc(Cl)c(Cl)c2)c2cc(Cl)ccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
