| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 3 |
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| Ligand | BDBM50030502 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_141442 (CHEMBL750215) |
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| IC50 | 239±n/a nM |
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| Citation |  Michne, WF; Guiles, JW; Treasurywala, AM; Castonguay, LA; Weigelt, CA; Oconnor, B; Volberg, WA; Grant, AM; Chadwick, CC; Krafte, DS Novel inhibitors of potassium ion channels on human T lymphocytes. J Med Chem38:1877-83 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 3 |
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| Name: | Potassium voltage-gated channel subfamily A member 3 |
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| Synonyms: | HGK5 | HLK3 | HPCN3 | HuKIII | KCNA3 | KCNA3_HUMAN | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63835.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1513935 |
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| Residue: | 575 |
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| Sequence: | MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
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| BDBM50030502 |
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| n/a |
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| Name | BDBM50030502 |
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| Synonyms: | CHEMBL299451 | [1-(4-Chloro-benzyl)-7-trifluoromethyl-1H-quinolin-(4E)-ylidene]-pentyl-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22ClF3N2 |
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| Mol. Mass. | 406.872 |
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| SMILES | CCCCC\N=c1/ccn(Cc2ccc(Cl)cc2)c2cc(ccc12)C(F)(F)F |
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| Structure | 
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