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TargetPotassium voltage-gated channel subfamily A member 3
LigandBDBM50030525
Substrate/Competitorn/a
Meas. Tech.ChEMBL_141442 (CHEMBL750215)
IC50>5000±n/a nM
Citation Michne, WF; Guiles, JW; Treasurywala, AM; Castonguay, LA; Weigelt, CA; Oconnor, B; Volberg, WA; Grant, AM; Chadwick, CC; Krafte, DS Novel inhibitors of potassium ion channels on human T lymphocytes. J Med Chem38:1877-83 (1995) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Potassium voltage-gated channel subfamily A member 3
Name:Potassium voltage-gated channel subfamily A member 3
Synonyms:HGK5 | HLK3 | HPCN3 | HuKIII | KCNA3 | KCNA3_HUMAN | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.3
Type:PROTEIN
Mol. Mass.:63835.47
Organism:Homo sapiens (Human)
Description:ChEMBL_1513935
Residue:575
Sequence:
MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50030525
n/a
NameBDBM50030525
Synonyms:1-Benzyl-4-hexyloxy-naphthalene | CHEMBL56808
TypeSmall organic molecule
Emp. Form.C23H26O
Mol. Mass.318.4519
SMILESCCCCCCOc1ccc(Cc2ccccc2)c2ccccc12
Structure
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