Reaction Details |
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Target | Serine protease 1 |
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Ligand | BDBM50031245 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_213087 (CHEMBL815015) |
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Ki | 1900±n/a nM |
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Citation | Angliker, H Synthesis of tight binding inhibitors and their action on the proprotein-processing enzyme furin. J Med Chem38:4014-8 (1995) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Serine protease 1 |
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Name: | Serine protease 1 |
Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
Type: | Enzyme |
Mol. Mass.: | 26557.80 |
Organism: | Homo sapiens (Human) |
Description: | P07477 |
Residue: | 247 |
Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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BDBM50031245 |
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n/a |
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Name | BDBM50031245 |
Synonyms: | CHEMBL341266 | {2-[2-(3-{6-Amino-2-[2-(2-decylamino-5-guanidino-pentanoylamino)-3-methyl-butyrylamino]-hexanoylamino}-6-guanidino-2-oxo-hexylamino)-propionylamino]-3-methyl-butyrylamino}-acetic acid methyl ester |
Type | Small organic molecule |
Emp. Form. | C45H88N14O8 |
Mol. Mass. | 953.2692 |
SMILES | CCCCCCCCCCN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)OC |
Structure |
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