Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetDeoxyhypusine synthase
LigandBDBM50009355
Substrate/Competitorn/a
Meas. Tech.ChEMBL_53735 (CHEMBL663660)
IC50 235000±n/a nM
Citation Lee, YBPark, MHFolk, JE Diamine and triamine analogs and derivatives as inhibitors of deoxyhypusine synthase: synthesis and biological activity. J Med Chem38:3053-61 (1995) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Deoxyhypusine synthase
Name:Deoxyhypusine synthase
Synonyms:DHYS_RAT | Dhps
Type:PROTEIN
Mol. Mass.:40696.63
Organism:Rattus norvegicus
Description:ChEMBL_53735
Residue:369
Sequence:
MEGTPSGAAPSSALAAVLKHSSALPPESAQVQGYDFNRGVDYHALLEAYGTTGFQATNFG
RAVQQVNAMIEKKLEPLAVDEDHHEDLTQSRRPLTGCTIFLGYTSNLISSGIRETIRYLV
QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNDNYCKFE
DWLMPILDQMVQEQNTEGVKWTPSKMISRLGKEINNPESVYYWAHKNHIPVLSPALTDGS
LGDMIFFHSYKNPGLVLDIVEDLRLINMQAIFAKRTGMIILGGGVVKHHIANANLMRNGA
DYAVYINTAQEFDGSDSGARPDEAVSWGKIRMDAQPVKVYADASLVFPLLVAETFAQKAD
AFRAEKNED
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50009355
n/a
NameBDBM50009355
Synonyms:4-(3-Amino-propylsulfanyl)-butylamine | CHEMBL28866
TypeSmall organic molecule
Emp. Form.C7H18N2S
Mol. Mass.162.296
SMILESNCCCCSCCCN
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: