| Reaction Details |
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 | Report a problem with these data |
| Target | Deoxyhypusine synthase |
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| Ligand | BDBM50032479 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_53735 (CHEMBL663660) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Lee, YB; Park, MH; Folk, JE Diamine and triamine analogs and derivatives as inhibitors of deoxyhypusine synthase: synthesis and biological activity. J Med Chem38:3053-61 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Deoxyhypusine synthase |
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| Name: | Deoxyhypusine synthase |
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| Synonyms: | DHYS_RAT | Dhps |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40696.63 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_53735 |
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| Residue: | 369 |
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| Sequence: | MEGTPSGAAPSSALAAVLKHSSALPPESAQVQGYDFNRGVDYHALLEAYGTTGFQATNFG
RAVQQVNAMIEKKLEPLAVDEDHHEDLTQSRRPLTGCTIFLGYTSNLISSGIRETIRYLV
QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNDNYCKFE
DWLMPILDQMVQEQNTEGVKWTPSKMISRLGKEINNPESVYYWAHKNHIPVLSPALTDGS
LGDMIFFHSYKNPGLVLDIVEDLRLINMQAIFAKRTGMIILGGGVVKHHIANANLMRNGA
DYAVYINTAQEFDGSDSGARPDEAVSWGKIRMDAQPVKVYADASLVFPLLVAETFAQKAD
AFRAEKNED
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|
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| BDBM50032479 |
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| n/a |
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| Name | BDBM50032479 |
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| Synonyms: | 2-(5-Carbamimidoylsulfanyl-pentyl)-isothiourea | CHEMBL102715 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H16N4S2 |
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| Mol. Mass. | 220.359 |
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| SMILES | NC(=N)SCCCCCSC(N)=N |
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| Structure | 
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