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TargetDeoxyhypusine synthase
LigandBDBM50032486
Substrate/Competitorn/a
Meas. Tech.ChEMBL_53735 (CHEMBL663660)
IC50 63000±n/a nM
Citation Lee, YBPark, MHFolk, JE Diamine and triamine analogs and derivatives as inhibitors of deoxyhypusine synthase: synthesis and biological activity. J Med Chem38:3053-61 (1995) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Deoxyhypusine synthase
Name:Deoxyhypusine synthase
Synonyms:DHYS_RAT | Dhps
Type:PROTEIN
Mol. Mass.:40696.63
Organism:Rattus norvegicus
Description:ChEMBL_53735
Residue:369
Sequence:
MEGTPSGAAPSSALAAVLKHSSALPPESAQVQGYDFNRGVDYHALLEAYGTTGFQATNFG
RAVQQVNAMIEKKLEPLAVDEDHHEDLTQSRRPLTGCTIFLGYTSNLISSGIRETIRYLV
QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNDNYCKFE
DWLMPILDQMVQEQNTEGVKWTPSKMISRLGKEINNPESVYYWAHKNHIPVLSPALTDGS
LGDMIFFHSYKNPGLVLDIVEDLRLINMQAIFAKRTGMIILGGGVVKHHIANANLMRNGA
DYAVYINTAQEFDGSDSGARPDEAVSWGKIRMDAQPVKVYADASLVFPLLVAETFAQKAD
AFRAEKNED
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  Blast E-value cutoff:
BDBM50032486
n/a
NameBDBM50032486
Synonyms:CHEMBL322423 | N*1*-(7-Amino-heptyl)-heptane-1,7-diamine
TypeSmall organic molecule
Emp. Form.C14H33N3
Mol. Mass.243.4319
SMILESNCCCCCCCNCCCCCCCN
Structure
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