| Reaction Details |
|---|
 | Report a problem with these data |
| Target | NADH-ubiquinone oxidoreductase chain 1 |
|---|
| Ligand | BDBM50411905 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_918171 (CHEMBL3060413) |
|---|
| IC50 | 3.0±n/a nM |
|---|
| Citation |  Yabunaka, H; Kenmochi, A; Nakatogawa, Y; Sakamoto, K; Miyoshi, H Hybrid ubiquinone: novel inhibitor of mitochondrial complex I. Biochim Biophys Acta1556:106-12 (2002) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| NADH-ubiquinone oxidoreductase chain 1 |
|---|
| Name: | NADH-ubiquinone oxidoreductase chain 1 |
|---|
| Synonyms: | MT-ND1 | MTND1 | NADH Oxidase | NADH-ubiquinone oxidoreductase | NADH-ubiquinone oxidoreductase chain 1 | NADH1 | ND1 | NU1M_BOVIN |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 35672.63 |
|---|
| Organism: | Bos taurus (Bovine) |
|---|
| Description: | P03887 |
|---|
| Residue: | 318 |
|---|
| Sequence: | MFMINILMLIIPILLAVAFLTLVERKVLGYMQLRKGPNVVGPYGLLQPIADAIKLFIKEP
LRPATSSASMFILAPIMALGLALTMWIPLPMPYPLINMNLGVLFMLAMSSLAVYSILWSG
WASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMSGSFTLSTLITTQEQMWLILPAWP
LAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYANIIMMNIFTAI
LFLGTSHNPHMPELYTINFTIKSLLLTMSFLWIRASYPRFRYDQLMHLLWKNFLPLTLAL
CMWHVSLPILTSGIPPQT
|
|
|
|---|
| BDBM50411905 |
|---|
| n/a |
|---|
| Name | BDBM50411905 |
|---|
| Synonyms: | CHEMBL272733 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H37NO4 |
|---|
| Mol. Mass. | 415.5656 |
|---|
| SMILES | COc1nc(CC=C(C)C\C=C\C(\C)=C\[C@@H](C)[C@@H](O)C(\C)=C\C)c(C)c(O)c1OC |w:6.5| |
|---|
| Structure | 
|
|---|
Search and Browse
