| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nicotinic acetylcholine receptor alpha 5 subunit |
|---|
| Ligand | BDBM50143320 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_916315 (CHEMBL3081642) |
|---|
| IC50 | 2790±n/a nM |
|---|
| Citation |  Kagabu, S; Kiriyama, K; Nishiwaki, H; Kumamoto, Y; Tada, T; Nishimura, K Asymmetric chloronicotinyl insecticide, 1-[1-(6-chloro-3-pyridyl)ethyl]-2-nitroiminoimidazolidine: preparation, resolution and biological activities toward insects and their nerve preparations. Biosci Biotechnol Biochem67:980-8 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Nicotinic acetylcholine receptor alpha 5 subunit |
|---|
| Name: | Nicotinic acetylcholine receptor alpha 5 subunit |
|---|
| Synonyms: | Nicotinic acetylcholine receptor alpha 5 subunit | nAChRalpha5 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 88489.00 |
|---|
| Organism: | Musca domestica |
|---|
| Description: | ChEMBL_106552 |
|---|
| Residue: | 781 |
|---|
| Sequence: | MMWEMLILWAVHLSLTAIATLYANVRTALSQTAQQIVRAVIAATTLPIIQRIQQQQHETE
KQQQQLQHGKHVEDIHLPAAGARYASASSSRLPPSSADATIWPRAPPELPQTEKLSSAPP
PPSSSSTLLMQTKPAHKKPVHGRNFPPQQKNRMQPVSHLQYQQQQQQQLSLPSPAEPQPQ
HYKQQQQQQGQERLGQQVNINNITSSSNGGNTCSSNSFTATTSIAATTTTSILTLWQHCH
RRYRPHQLLPLLTTKGLNKYSWIFLLIYLNLSAKVCLAGYNEKRLLHDLLDTYNTLERPV
LNESDPLQLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGIKDLRIPP
HRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRC
EMKFGSWTYDGFQLDLQLQDETGGDISSYVLNGEWELLGVPGKRNEIYYNCCPEPYIDIT
FAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAE
TMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNADTHEMSEWIRVVFLCWLPW
ILRMHRPGRPIIMDFTSTPCSDTSSERKHQILSDVELKERSSKSLLANVLDIDDDFRNVR
PMTPGGTLPHNPAFYRTVYGYLENLQGDDGSIGPIGSTRMPDAVTHHTCIKTQTEYELSL
ILKEIRFITDQLRKEDEENGIANDWKFAAMVVDRLCLIIFTMFAILATIAVLLSAPHVIV
S
|
|
|
|---|
| BDBM50143320 |
|---|
| n/a |
|---|
| Name | BDBM50143320 |
|---|
| Synonyms: | (+)-epibatidine | (-)-1-epidatidine | (1S,2S,4R)-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | CHEMBL298517 | US9284322, (-)-epibatidine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H13ClN2 |
|---|
| Mol. Mass. | 208.687 |
|---|
| SMILES | Clc1ccc(cn1)[C@@H]1C[C@H]2CC[C@@H]1N2 |THB:4:7:13:11.10| |
|---|
| Structure | 
|
|---|
Search and Browse
