| Reaction Details |
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 | Report a problem with these data |
| Target | Collagenase ColG |
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| Ligand | BDBM50092158 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_916952 (CHEMBL3082946) |
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| IC50 | 185000±n/a nM |
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| Citation |  Morita, Y; Matsumura, E; Okabe, T; Shibata, M; Sugiura, M; Ohe, T; Tsujibo, H; Ishida, N; Inamori, Y Biological activity of tropolone. Biol Pharm Bull26:1487-90 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Collagenase ColG |
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| Name: | Collagenase ColG |
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| Synonyms: | 3.4.24.3 | COLG_HATHI | Class I collagenase | Collagenase (ChC) | Collagenase ColG | Gelatinase ColG | Microbial collagenase | class 1 collagenase | colG |
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| Type: | Enzyme |
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| Mol. Mass.: | 126246.16 |
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| Organism: | Clostridium histolyticum |
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| Description: | Q9S0X0 |
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| Residue: | 1118 |
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| Sequence: | MKKNILKILMDSYSKESKIQTVRRVTSVSLLAVYLTMNTSSLVLAKPIENTNDTSIKNVE
KLRNAPNEENSKKVEDSKNDKVEHVKNIEEAKVEQVAPEVKSKSTLRSASIANTNSEKYD
FEYLNGLSYTELTNLIKNIKWNQINGLFNYSTGSQKFFGDKNRVQAIINALQESGRTYTA
NDMKGIETFTEVLRAGFYLGYYNDGLSYLNDRNFQDKCIPAMIAIQKNPNFKLGTAVQDE
VITSLGKLIGNASANAEVVNNCVPVLKQFRENLNQYAPDYVKGTAVNELIKGIEFDFSGA
AYEKDVKTMPWYGKIDPFINELKALGLYGNITSATEWASDVGIYYLSKFGLYSTNRNDIV
QSLEKAVDMYKYGKIAFVAMERITWDYDGIGSNGKKVDHDKFLDDAEKHYLPKTYTFDNG
TFIIRAGDKVSEEKIKRLYWASREVKSQFHRVVGNDKALEVGNADDVLTMKIFNSPEEYK
FNTNINGVSTDNGGLYIEPRGTFYTYERTPQQSIFSLEELFRHEYTHYLQARYLVDGLWG
QGPFYEKNRLTWFDEGTAEFFAGSTRTSGVLPRKSILGYLAKDKVDHRYSLKKTLNSGYD
DSDWMFYNYGFAVAHYLYEKDMPTFIKMNKAILNTDVKSYDEIIKKLSDDANKNTEYQNH
IQELADKYQGAGIPLVSDDYLKDHGYKKASEVYSEISKAASLTNTSVTAEKSQYFNTFTL
RGTYTGETSKGEFKDWDEMSKKLDGTLESLAKNSWSGYKTLTAYFTNYRVTSDNKVQYDV
VFHGVLTDNADISNNKAPIAKVTGPSTGAVGRNIEFSGKDSKDEDGKIVSYDWDFGDGAT
SRGKNSVHAYKKAGTYNVTLKVTDDKGATATESFTIEIKNEDTTTPITKEMEPNDDIKEA
NGPIVEGVTVKGDLNGSDDADTFYFDVKEDGDVTIELPYSGSSNFTWLVYKEGDDQNHIA
SGIDKNNSKVGTFKSTKGRHYVFIYKHDSASNISYSLNIKGLGNEKLKEKENNDSSDKAT
VIPNFNTTMQGSLLGDDSRDYYSFEVKEEGEVNIELDKKDEFGVTWTLHPESNINDRITY
GQVDGNKVSNKVKLRPGKYYLLVYKYSGSGNYELRVNK
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| BDBM50092158 |
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| n/a |
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| Name | BDBM50092158 |
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| Synonyms: | 1,10-phenanthroline | CHEMBL415879 | US10669227, Compound 1,10-phenanthroline | US11608309, Compound 1,10-phenanthroline | US9187406, 1,10-phenanthroline | cid_1318 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H8N2 |
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| Mol. Mass. | 180.2053 |
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| SMILES | c1cnc2c(c1)ccc1cccnc21 |
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| Structure | 
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