| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50033039 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_86913 (CHEMBL699051) |
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| Ki | 42±n/a nM |
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| Citation |  Ganellin, CR; Hosseini, SK; Khalaf, YS; Tertiuk, W; Arrang, JM; Garbarg, M; Ligneau, X; Schwartz, JC Design of potent non-thiourea H3-receptor histamine antagonists. J Med Chem38:3342-50 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50033039 |
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| n/a |
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| Name | BDBM50033039 |
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| Synonyms: | 6-[2-(1H-Imidazol-4-yl)-ethylamino]-nicotinic acid methyl ester | CHEMBL112349 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H14N4O2 |
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| Mol. Mass. | 246.2652 |
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| SMILES | COC(=O)c1ccc(NCCc2cnc[nH]2)nc1 |
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| Structure | 
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