| Reaction Details |
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 | Report a problem with these data |
| Target | Ecdysone receptor |
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| Ligand | BDBM50488450 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_923770 (CHEMBL3070748) |
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| EC50 | 5.4±n/a nM |
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| Citation |  Soin, T; De Geyter, E; Mosallanejad, H; Iga, M; Martín, D; Ozaki, S; Kitsuda, S; Harada, T; Miyagawa, H; Stefanou, D; Kotzia, G; Efrose, R; Labropoulou, V; Geelen, D; Iatrou, K; Nakagawa, Y; Janssen, CR; Smagghe, G; Swevers, L Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays. Pest Manag Sci66:526-35 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ecdysone receptor |
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| Name: | Ecdysone receptor |
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| Synonyms: | Ecdysone receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 65589.52 |
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| Organism: | Spodoptera littoralis |
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| Description: | ChEMBL_105550 |
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| Residue: | 585 |
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| Sequence: | MSIESRLDSLVRGKSEVKAFAGGCPSALLDTGACDTLADMRRRWYNNGGFQTLRMLEESS
SEVTSSSALGLPPAMVMSPESLASPEYGGLELWGYEDGLTTYSMAQSLGSCTMEQQQQPQ
QQQQPQQTQPLPSMPLPMPPTTPKSENESMSSGREELSPASSVNGCSTDGEARRQKKGPA
PRQQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKNAVYICKFGHACEMDMYMRRKC
QECRLKKCLAVGMRPECVVPENQCAMKRKEKKAQREKDKLPVSTTTVDDHMPPIMQCDPP
PPEAARIHEVVPRFLTEKILEQNRLKNVPPLTTNQKSLIARLVWYQEGYEQPSEEDLKRV
TQSDEDDEESDMPFRQITEMTILTVQLIVEFAKGLPGFAKISQSDQITLLKACSSEVMML
RVARRYDASTDSVLFANNQAYTRDNYRKAGMAYVIEDLLHFCRCMYAMSMDNVQYALLTA
IVIFSDRPGLEQPLLVEEIQRYYLNTLRMYVLNQHSASPRCPVVFGKILGVLTELRTLGM
QNSNMCISLKLKNRKLPPFLEEIWDVADVSTTATPAAPVTETAAL
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| BDBM50488450 |
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| n/a |
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| Name | BDBM50488450 |
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| Synonyms: | CHEMBL2286445 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25ClN2O3 |
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| Mol. Mass. | 400.899 |
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| SMILES | Cc1c2CCCOc2ccc1C(=O)NN(C(=O)c1ccccc1Cl)C(C)(C)C |
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| Structure | 
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