| Reaction Details |
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 | Report a problem with these data |
| Target | Ecdysone receptor |
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| Ligand | BDBM50488517 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_925676 (CHEMBL3070722) |
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| EC50 | 105±n/a nM |
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| Citation |  Soin, T; Swevers, L; Kotzia, G; Iatrou, K; Janssen, CR; Rougé, P; Harada, T; Nakagawa, Y; Smagghe, G Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays. Pest Manag Sci66:1215-29 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ecdysone receptor |
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| Name: | Ecdysone receptor |
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| Synonyms: | 20-hydroxy-ecdysone receptor | 20E receptor | ECR_BOMMO | EcR | EcRH | Ecdysteroid receptor | NR1H1 | Nuclear receptor subfamily 1 group H member 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 68199.29 |
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| Organism: | Bombyx mori |
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| Description: | ChEMBL_65456 |
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| Residue: | 606 |
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| Sequence: | MRVENVDNVSFALNGRADEWCMSVETRLDSLVREKSEVKAYVGGCPSVITDAGAYDALFD
MRRRWSNNGGFPLRMLEESSSEVTSSSALGLPPAMVMSPESLASPEYRALELWSYDDGIT
YNTAQSLLGACNMQQQQLQPQQPHPAPPTLPTMPLPMPPTTPKSENESMSSGREELSPAS
SINGCSADADARRQKKGPAPRQQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKNAV
YICKFGHACEMDMYMRRKCQECRLKKCLAVGMRPECVIQEPSKNKDRQRQKKDKGILLPV
STTTVEDHMPPIMQCDPPPPEAARIHEVVPRYLSEKLMEQNRQKNIPPLSANQKSLIARL
VWYQEGYEQPSDEDLKRVTQTWQSDEEDEESDLPFRQITEMTILTVQLIVEFAKGLPGFS
KISQSDQITLLKASSSEVMMLRVARRYDAASDSVLFANNKAYTRDNYRQGGMAYVIEDLL
HFCRCMFAMGMDNVHFALLTAIVIFSDRPGLEQPSLVEEIQRYYLNTLRIYIINQNSASS
RCAVIYGRILSVLTELRTLGTQNSNMCISLKLKNRKLPPFLEEIWDVAEVATTHPTVLPP
TNPVVL
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| BDBM50488517 |
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| n/a |
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| Name | BDBM50488517 |
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| Synonyms: | CHEMBL2286738 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19IN2O2 |
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| Mol. Mass. | 422.2601 |
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| SMILES | CC(C)(C)N(NC(=O)c1ccccc1)C(=O)c1ccccc1I |
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| Structure | 
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